Genistein is effective in inhibiting Orf virus infection in vitro by targeting viral RNA polymerase subunit RPO30 protein

Orf virus (ORFV), a typical member of the genus Parapoxvirus, Poxvirus family, causes a contagious pustular dermatitis in sheep, goats, and humans.Poxviruses encode a multisubunit DNA-dependent RNA polymerase (vRNAP) that carries out Natural Leather Strop viral gene expression in the host cytoplasm, which is a viral factor essential to poxvirus rep

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